THE IMPACT OF UPF1 ATP MIMETICS ON THE MUTANT IMMUNOPEPTIDOME – A NEW OPUS PROJECT AT ICCVS

About the research: A critical cellular surveillance mechanism that recognizes and eliminates aberrant mRNAs containing premature termination codons (PTC) is termed as nonsense-mediated mRNA decay (NMD). PTCs containing mRNAs are rapidly degraded by the NMD machinery. Active NMD renders many dominant ...