Laboratory of RNA Biology
THE SCOPE OF THE RESEARCH
Research in the Konarska lab focuses on mechanisms of action of the spliceosome, a complex molecular machine responsible for pre-mRNA splicing. The work focuses on the study of dynamic interactions inside the spliceosome during splicing catalysis, influencing the location of the splicing sites in the active center, and thus determining the specificity of splicing. These studies help to understand the molecular basis of the course of alternative splicing typical of higher eukaryotes.