Laboratory of Mitochondrial Biogenesis
Prof. Agnieszka Chacińska, PhD
THE SCOPE OF THE RESEARCH
The biogenesis of mitochondria relies on efficient import, sorting, and maturation of proteins, governed by a conserved protein translocation system. The Laboratory of Mitochondrial Biogenesis explores new links between protein transport mechanisms and mitochondrial protein homeostasis, involving crosstalk between the cytosol and mitochondrial compartments. This research will shed light on complex and dynamic processes involved in the formation of functional organelles and the maintenance of cellular protein homeostasis, failures of which can lead to pathologies, such as neurodegeneration.