Laboratory of Lipids and Chronobiology
Abdehalim Azzi, PhD
Dr. Abdelhalim Azzi Abdelhalim Azzi completed his PhD in 2014 under the supervision of Prof. Steven A. Brown at the University of Zurich, Switzerland. He then joined the laboratory of Prof. Stéphane Schurmans at the GIGA research center in Belgium as a visiting scientist and later joined the laboratory of Prof. Xu Wu as a research fellow at the Massachusetts General Hospital, Harvard Medical School, USA where he studied the crosstalk between the hippo signaling pathway and circadian clock. He joined IMOL in 2021 as principal investigator.
THE SCOPE OF THE RESEARCH
Dr. Azzi’s lab is interested in understanding the role of phosphoinositide signaling in regulation of circadian metabolic processes. The main aim of the research is to examine how daily spatiotemporal variations in phosphoinositides affect daily carbohydrate and lipid metabolism. The lab focuses currently on two system models, the 5-phosphatase SHIP2 and the phosphatidylinositol 3-kinase isoform γ (PI3K-C2γ).